Citrullinated ?-Enolase (R8 + R14) (1-19)-biotin Peptide

CAT N°: 37627
Price:

337.00 286.45

Citrullinated ?-Enolase (R8 + R14) (1-19)-biotin peptide is a biotinylated and citrullinated form of a 19-amino acid N-terminal peptide fragment of ?-enolase, a glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate.{42086} ?-Enolase also functions as a cell surface receptor for plasminogen on pathogens and activated immune cells, as an oxidative stress protein in endothelial cells, and as a chromatin binding partner to facilitate transcription.{42087,42088,42089} ?-Enolase is an autoantigen in asthma, Hashimoto’s encephalopathy, and rheumatoid arthritis, and has been found in the serum of pediatric patients with juvenile idiopathic arthritis.{42090,42091,42092,36062} ?-Enolase is also subject to citrullination by peptidyl arginine deiminases (PADs) and citrullinated ?-enolase has been found in the synovial fluid of rheumatoid arthritis patients.{42092} Cayman’s Citrullinated ?-Enolase (R8 + R14) (1-19)-biotin Peptide is intended for use in the detection of autoantibodies against ?-enolase citrullinated at R8 and R13.

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