2-Amino-3,8-<wbr/>dimethyl<wbr/>imidazo-[4,5-<wbr/>f]-quinoxaline

2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline

CAT N°: 34812
Price:

102.00

2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline (MeIQx) is a food-derived carcinogen that has been found in high temperature-cooked fish and meats.{49714} It is activated by hydroxylation and subsequent O-acetylation via the cytochrome P450 (CYP) isoform CYP1A2 and N-acetyltransferase 2, respectively, in UV5 cells expressing the human enzymes to a metabolite that reacts with DNA to form adducts.{39298} MeIQx (200 and 400 ppm in the diet) induces tumor formation in rats.{62397}

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