ML-309 (hydro<wbr/>chloride)

ML-309 (hydrochloride)

CAT N°: 21519
Price:

59.00

ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1).{42529} It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively). ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM).

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